I saw another thread below entitled "Portable Thunderbird hangs in Mavericks." I believe this is related to the same issue however that thread did not present an answer to this question. I also tried the terminal command someone wrote in that thread and it did not work. Here is the problem clearly:
As a part of the new security features of OSX Mavericks, it seems to run a "one time" check when you install new apps for things you want the app to access. In this case, it runs the check for portable thunderbird to access contacts and it asks me if I want to grant the application permission to access contacts. Normally, this is a one-time thing, but because portable thunderbird is "new" every time it is mounted on the drive, it runs this check every time. I found this out because I watch it appear and disappear from the privacy and security window under system preferences when I mount and un-mount. It wouldn't be so annoying except that running this check causes the app to hang a while, sometimes for a few minutes, before the dialogue window pops up and I can make the choice, after which it runs fine.
Any ideas on a work around for this? A terminal command of some kind?